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. 2020 May 16;18(5):262. doi: 10.3390/md18050262

Table 3.

The effect of the treatment on the pathology score and the goblet and epithelial cell % in the colonic tissue (least square means with their standard errors).

Treatment SEM Contrasts
Control Basal DSS Laminarin DSS Chitosan DSS 1 2 3
Pathology score 1.0 2.0 1.7 1.9 0.330 * NS NS
Goblet cell % 14.9 27.02 23.12 22.54 2.72 ** NS NS
Epithelial cell % 85.1 72.99 76.88 77.46 2.72 ** NS NS

The pathology scores range from 1–5 as follows: 1 = normal, non-ulcerating epithelium with a reduced lamina proprial cell infiltration; 2 = normal with a lamina proprial cell infiltration within the normal spectrum; 3 = colonic samples with focal (single) regions of ulceration; 4 = samples with multiple foci of ulceration interspersed between regions of normal colon and 5 = samples with diffuse ulceration. Contrasts: (1) Control vs. Basal DSS; (2) Basal DSS vs. Laminarin DSS; (3) Basal DSS vs. Chitosan DSS; NS, non-significant; * p < 0.05; ** p < 0.01.