Table 4.
The effects of the treatment on gene expression in the colon (least square means with their standard errors).
| Treatment | SEM | Contrasts | ||||||
|---|---|---|---|---|---|---|---|---|
| Control | Basal DSS | Laminarin DSS | Chitosan DSS | 1 | 2 | 3 | ||
| MMP1 | 0.245 | 2.142 | 0.857 | 2.371 | 0.646 | * | NS | NS |
| IL13 | 0.634 | 1.033 | 0.916 | 0.870 | 0.103 | * | NS | NS |
| IL23A | 0.487 | 0.975 | 1.052 | 0.740 | 0.153 | * | NS | NS |
| MMP2 | 0.476 | 1.113 | 0.945 | 1.079 | 0.268 | NS | NS | NS |
| MMP9 | 0.525 | 1.065 | 0.758 | 1.164 | 0.256 | NS | NS | NS |
| CLEC7A | 0.929 | 1.453 | 0.943 | 1.236 | 0.330 | NS | NS | NS |
| TLR4 | 0.904 | 1.046 | 1.554 | 1.359 | 0.350 | NS | NS | NS |
| TJP1 | 0.895 | 0.930 | 0.867 | 0.924 | 0.056 | NS | NS | NS |
| CDH1 | 0.891 | 1.122 | 1.017 | 1.022 | 0.112 | NS | NS | NS |
| MARVELD2 | 1.480 | 1.566 | 1.688 | 1.765 | 0.451 | NS | NS | NS |
| IL10 | 0.587 | 0.906 | 1.019 | 0.962 | 0.159 | NS | NS | NS |
| IL17A | 0.808 | 0.747 | 1.157 | 1.217 | 0.288 | NS | NS | NS |
| IL6 | 0.310 | 1.725 | 1.356 | 1.269 | 0.549 | NS | NS | NS |
| IL1B | 0.428 | 0.905 | 1.170 | 1.451 | 0.322 | NS | NS | NS |
| IFNG | 1.457 | 0.899 | 1.081 | 1.243 | 0.425 | NS | NS | NS |
| TGFB1 | 0.925 | 0.870 | 0.913 | 0.944 | 0.156 | NS | NS | NS |
| MUC4 | 1.393 | 0.780 | 0.931 | 1.337 | 0.247 | NS | NS | NS |
MMP1, matrix metalloproteinase 1; IL13, interleukin 13; IL23A, interleukin 23 subunit alpha; MMP2, matrix metalloproteinase 2; MMP9, matrix metalloproteinase 9; CLEC7A, C-type lectin domain containing 7A; TLR4, Toll-like receptor 4; TJP1, tight junction protein 1; CDH1, cadherin 1; MARVELD2, MARVEL domain containing 2; IL10, interleukin 10; IL17A, interleukin 17A; IL6, interleukin 6; IL1B, interleukin 1B; IFNG, interferon gamma; TGFB1, transforming growth factor beta 1; MUC4, mucin 4; Contrasts: (1) Control vs. Basal DSS; (2) Basal DSS vs. Laminarin DSS; (3) Basal DSS vs. Chitosan DSS; NS, non-significant; * p < 0.05.