Table 2.
Association of metabolic biomarkers with long-term blood pressure variability indexes in multivariable liner regression
|
Unadjusted |
Model 1 |
Model 2 |
|||||||
| β (SE) | P value | R2, % | β (SE) | P value | R2, % | β (SE) | P value | R2, % | |
| Waist circumference | |||||||||
| ARVSBP | 0.046 (0.046) | 0.31 | 0.0 | 0.039 (0.044) | 0.38 | 7.9 | −0.002 (0.026) | 0.95 | 68.6 |
| ARVDBP | 0.157 (0.049) | < 0.01 | 0.9 | 0.078 (0.048) | 0.10 | 8.3 | −0.004 (0.028) | 0.88 | 68.9 |
| SDSBP | 0.071 (0.060) | 0.23 | 0.1 | 0.050 (0.058) | 0.38 | 8.1 | −0.021 (0.034) | 0.53 | 68.9 |
| SDDBP | 0.220 (0.065) | < 0.01 | 1.0 | 0.100 (0.064) | 0.11 | 8.3 | −0.003 (0.037) | 0.92 | 68.9 |
| Serum uric acid | |||||||||
| ARVSBP | 0.009 (0.008) | 0.27 | 0.1 | 0.009 (0.008) | 0.30 | 1.6 | 0.011 (0.008) | 0.18 | 11.0 |
| ARVDBP | 0.022 (0.009) | 0.01 | 0.5 | 0.016 (0.009) | 0.07 | 1.8 | 0.012 (0.008) | 0.16 | 11.0 |
| SDSBP | 0.020 (0.011) | 0.06 | 0.3 | 0.019 (0.011) | 0.08 | 1.8 | 0.019 (0.010) | 0.05 | 11.1 |
| SDDBP | 0.038 (0.012) | < 0.01 | 1.0 | 0.030 (0.012) | 0.01 | 2.1 | 0.027 (0.011) | 0.01 | 11.3 |
| Serum triglycerides | |||||||||
| ARVSBP | 0.031 (0.673) | 0.96 | 0.0 | −0.014 (0.663) | 0.98 | 3.0 | 0.310 (0.615) | 0.61 | 18.2 |
| ARVDBP | 1.155 (0.712) | 0.10 | 0.2 | 0.473 (0.715) | 0.50 | 3.0 | 0.343 (0.660) | 0.60 | 18.2 |
| SDSBP | −0.003 (0.871) | 0.99 | 0.0 | −0.121 (0.860) | 0.88 | 3.0 | 0.141 (0.796) | 0.86 | 18.2 |
| SDDBP | 1.545 (0.946) | 0.10 | 0.2 | 0.493 (0.954) | 0.60 | 3.0 | 0.478 (0.881) | 0.58 | 18.2 |
| Fasting glucose | |||||||||
| ARVSBP | −0.008 (0.086) | 0.92 | 0.0 | −0.011 (0.086) | 0.90 | 0.5 | 0.006 (0.084) | 0.94 | 5.2 |
| ARVDBP | 0.024 (0.091) | 0.79 | 0.0 | −0.014 (0.092) | 0.88 | 0.5 | −0.033 (0.090) | 0.71 | 5.2 |
| SDSBP | 0.036 (0.111) | 0.74 | 0.0 | 0.029 (0.111) | 0.79 | 0.5 | 0.028 (0.109) | 0.79 | 5.2 |
| SDDBP | 0.126 (0.120) | 0.29 | 0.0 | 0.072 (0.123) | 0.55 | 0.2 | 0.058 (0.121) | 0.62 | 4.5 |
| High-density lipoprotein | |||||||||
| ARVSBP | −0.134 (0.063) | 0.03 | 0.4 | −0.131 (0.063) | 0.03 | 0.9 | −0.080 (0.060) | 0.18 | 11.3 |
| ARVDBP | −0.062 (0.067) | 0.36 | 0.1 | −0.045 (0.068) | 0.51 | 0.6 | 0.004 (0.065) | 0.95 | 11.2 |
| SDSBP | −0.130 (0.082) | 0.11 | 0.2 | −0.121 (0.082) | 0.14 | 0.7 | −0.058 (0.078) | 0.45 | 11.2 |
| SDDBP | −0.120 (0.089) | 0.18 | 0.1 | −0.095 (0.091) | 0.29 | 0.3 | −0.022 (0.087) | 0.79 | 10.4 |
Data are presented as β (SE) using Pearson’s correlation coefficient for Model 2: SBP and DBP adjustments; Model 3: The covariates in Model 2, age, BMI, total cholesterol, exercise frequency, current drinker and current smoker adjustments. SBP: Systolic blood pressure; DBP: Diastolic blood pressure; ARV: Average real variability; SD: Standard deviation; SE: Standard errors.