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. 2020 May 18;12(5):1277. doi: 10.3390/cancers12051277

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Proteomic analysis of DXR or saline-treated placentae (control samples). Proteins from four DXR- or saline-exposed placentae (from 3 pregnant mice in each group) were identified, quantified, and their intensities were normalized. (A) Summary table of proteins that exhibit significant changes in their intensity (false discovery rate (FDR) < 0.05) and are potentially related to vascular toxicity; (B) STRING (Search Tool for Retrieval of Interacting Genes/Proteins) database analysis, as elaborated in the Methods section, of functional associations network of the vascular toxicity related proteins. Platelet degranulation pathway proteins are colored in red.