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. 2020 May 25;22(5):e15977. doi: 10.2196/15977

Table 2.

Overall effect sizes and stratification by study design features.

Studies Population, n Cohen d (95% CI) P value Qw (P value)a I2 (%) Qb (P valueb)
UAIc N/Ad

All studies at endpoint 35 −.32 (−.43 to −.20) <.001 203.32 (<.001) 83.3

Studies at endpoint without outliers 33 −.21 (−.28 to −.14) <.001 65.08 (<.001) 50.8

Partner-specific UAIe,f,g N/A


With main partners 6 −.42 (−.57 to −.27) <.001 5.18 (.39) 3.4


With nonmain partners 9 −.20 (−.27 to −.13) <.001 7.78 (.46) 0.0

Follow-up periodf N/A


Postintervention 16 −.22 (−.36 to −.08) .001 48.02 (<.001) 68.8


≤3 monthse 19 −.21 (−.28 to −.12) <.001 35.92 (.007) 49.9


>3 monthse 6 −.26 (−.43 to −.08) .004 11.60 (.04) 56.9

Comparison statuse,g 13.38 (<.001)


Concurrent 19 −.10 (−.18 to −.03) .004 24.29 (.14) 25.9


Preintervention 14 −.31 (−.40 to −.23) <.001 18.16 (.15) 28.4
HIV testing

All studies at end point 23 .41 (.28 to .54) <.001 137.43 (<.001) 84.0

Studies at end point without outliers 20 .38 (.27 to .48) <.001 53.04 (<.001) 64.2

Follow-up periodf N/A


Postintervention 15 .46 (.38 to .55) <.001 23.49 (.05) 40.4


≤3 monthse 8 .24 (.09 to .40) .002 12.57 (.08) 44.3


>3 months 1 .47 (.25 to .69) <.001 N/A N/A

Comparison statuse,g 0.42 (.52)


Concurrent 11 .39 (.25 to .53) <.001 36.67 (<.001) 72.7


Preintervention 9 .33 (.22 to .44) <.001 9.14 (.33) 12.4
Multiple sex partnership

All studies at endpoint 6 −.26 (−.48 to −.05) .02 12.56 (.03) 60.2

Follow-up periodf N/A


Postintervention 2 −.18 (−.33 to −.03) .02 0.08 (.78) 0.0


≤3 months 3 −.19 (−.75 to .37) .50 11.65 (.003) 82.8


>3 months 2 −.36 (−.56 to −.16) <.001 0.34 (.56) 0.0

aQw denotes the degree of within-group heterogeneity.

bQb denotes the degree of between-group difference in the pooled effect sizes.

cUAI: unprotected anal intercourse.

dN/A: not applicable.

eStudies with exclusion of outliers.

fNon-nested groupings: one study could contribute to more than one grouping.

gEffect sizes at the endpoint were pooled.