Table 5.
Multivariable Cox proportional hazard model predicting DM as a function of a 5-protein classifier to complement biopsy SOC variables in study testing cohort.
Variable | Model 1 * | Model 2 ** | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p Value | HR | 95% CI | p Value | |
Age at diagnosis | 1.00 | 0.93–1.07 | 0.898 | 1.03 | 0.96–1.11 | 0.407 |
Race (AA vs. CA) | 0.94 | 0.33–2.74 | 0.916 | 1.59 | 0.54–4.64 | 0.396 |
Risk (intermediate vs. low) | 2.31 | 0.69–7.76 | 0.176 | 1.49 | 0.41–5.47 | 0.545 |
Risk (high vs. low) | 4.68 | 1.14–19.22 | 0.032 | 2.29 | 0.52–10.16 | 0.274 |
5-protein classifier (high vs. low) | 5.09 | 1.11–23.38 | 0.036 | 1.03 | 1.02–1.05 | <0.001 |
* Model 1: Classifier was modeled dichotomously, using median split 8.3. ** Model 2: Classifier was modeled as continuous.