Table 1.
Features of patients and primary cells isolated from patients affected by HGSOC. Characteristics of the cohort of patients affected by HGSOC, enrolled in the study at the Department of Obstetrics and Gynecology of IRCCS Burlo Garofolo (n = 13). Cells isolated from the first six patients were frozen before using them for experiments. Values of CA-125 are expressed as UI/l. Notes: np = not present; stage: in ovarian cancer, stages are expressed in Roman numerals and each stage is further divided into A, B and C.
| Patient Code | Age (Years) | Stage | Peritoneal Carcinosis | Ascites | Pleural Effusion | BRCA Germinal Mutation | CA125 Pre-Treatment (UI/L) |
|---|---|---|---|---|---|---|---|
| 1 | 64 | IIIC | + | + | - | no | 490 |
| 2 | 51 | IIIC | + | + | - | no | 168 |
| 3 | 68 | IIIC | + | + | - | yes | 649 |
| 4 | 58 | IIIC | + | + | - | no | 108 |
| 5 | 64 | IIIC | + | + | + | no | 1116 |
| 6 | 58 | IIIC | + | + | + | np | 118 |
| 7 | 76 | IIB | + | + | + | np | 7172 |
| 8 | 71 | IIIA | + | np | - | np | 20 |
| 9 | 55 | IIIA | + | - | - | yes | 290 |
| 10 | 73 | IIB | + | + | - | no | 1232 |
| 11 | 67 | IIB | - | - | - | yes | 16 |
| 12 | 69 | IIIC | + | + | - | np | 3175 |
| 13 | 60 | IIB | + | - | - | np | 70 |