Effects of pterostilbene and gemcitabine cotreatment on MIA PaCa-2 and MIA PaCa-2 GEMR cell viability. Cells were treated with 50 or 75 μM pterostilbene combined with gemcitabine for 72 h. The cell viability of (A) MIA PaCa-2 and (B) MIA PaCa-2 GEMR cells was analyzed by MTT assay. The results are expressed as the mean ± SD (n = 3). p values were considered statistically significant when *p < 0.05, **p < 0.01, and ***p < 0.001 compared with untreated control. The values were considered statistically significant at †p < 0.05 and †††p < 0.001, compared with the gemcitabine group. The values were considered statistically significant at ‡p < 0.05, ‡‡p < 0.01 and ‡‡‡p < 0.001, compared with the pterostilbene group.