Effect of the peptides on LAMP-1 protein expression: (a) Western blotting analysis of LAMP-1 after treatment with PLVE and VLPE (20 μM) for 24, 48, and 72 h in 769-P cells. (b) Confocal microscopy evaluation of LAMP-1 expression after 48 and 72 h of treatment with PLVE and VLPE (20 μM) in 769-P cells. (c) Western blotting analysis of LAMP-1 after treatment with PLVE and VLPE (20 μM) for 24, 48, and 72 h in A498 cells. (d) Confocal microscopy evaluation of LAMP-1 expression after 48 and 72 h of treatment with PLVE and VLPE (20 μM) in A498 cells. Data are represented as mean ± SD of at least three replicates. Significance was calculated through one-way ANOVA followed by Dunnet’s test. * = p < 0.05, ** = p < 0.01, *** = p < 0.001.