TME |
tumor microenvironment |
IBD |
inflammatory bowels disease |
MPs |
mononuclear phagocytes |
PAMPs/DAMPs |
pathogen- or damage-associated molecular patterns |
TREM 1 |
triggering receptor expressed on myeloid cells |
Mn |
monocytes |
TAMs |
tumor-associated macrophages |
TADCs |
tumor-associated dendritic cells |
ROS |
reactive oxygen species |
NO |
nitric oxide |
pO2 |
partial oxygen pressure |
PRRs |
pattern recognition receptors |
IRS |
immunoregulatory signaling |
ADCC |
Ab-dependent cell-mediated cytotoxicity |
TLRs |
toll-like receptors |
MSR |
macrophage scavenger receptor 1 |
MARCO |
macrophage receptor with collagenous structure |
NSCLC |
non-small cell lung cancer |
SIRPα |
signal regulatory protein-alpha |
CD47 |
cluster of differentiation 47 |
PD1 |
programmed cell death-1 |
PDL1 |
programmed cell death-1 ligand |
LILRB1 |
leukocyte immunoglobulin-like receptor B1 |
β2M |
β2-microglobulin |
TIM-3 |
T cell Ig and mucin domain 3 |
HMGB1 |
high mobility group box 1 |
mAbs |
monoclonal antibodies |
FcRs |
Fc region of Igs |
ADP |
Ab-dependent phagocytosis |
CYT |
cytoplasmic tail |
DAP12 |
DNA activating protein 12 |
ITAM |
immunoreceptor tyrosine-based activatory motif |
sTREM-1 |
soluble TREM-1 |
MMP |
metalloproteinase |
LCs |
Langerhans cells |
HRE |
hypoxia response element |
HIF1 |
hypoxia-inducible transcription factor |
HCC |
hepatocellular carcinoma |
siRNA |
small interfering RNA |
HSCs |
hepatic stellate cells |