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. 2020 May 23;12(5):1337. doi: 10.3390/cancers12051337
TME tumor microenvironment
IBD inflammatory bowels disease
MPs mononuclear phagocytes
PAMPs/DAMPs pathogen- or damage-associated molecular patterns
TREM 1 triggering receptor expressed on myeloid cells
Mn monocytes
TAMs tumor-associated macrophages
TADCs tumor-associated dendritic cells
ROS reactive oxygen species
NO nitric oxide
pO2 partial oxygen pressure
PRRs pattern recognition receptors
IRS immunoregulatory signaling
ADCC Ab-dependent cell-mediated cytotoxicity
TLRs toll-like receptors
MSR macrophage scavenger receptor 1
MARCO macrophage receptor with collagenous structure
NSCLC non-small cell lung cancer
SIRPα signal regulatory protein-alpha
CD47 cluster of differentiation 47
PD1 programmed cell death-1
PDL1 programmed cell death-1 ligand
LILRB1 leukocyte immunoglobulin-like receptor B1
β2M β2-microglobulin
TIM-3 T cell Ig and mucin domain 3
HMGB1 high mobility group box 1
mAbs monoclonal antibodies
FcRs Fc region of Igs
ADP Ab-dependent phagocytosis
CYT cytoplasmic tail
DAP12 DNA activating protein 12
ITAM immunoreceptor tyrosine-based activatory motif
sTREM-1 soluble TREM-1
MMP metalloproteinase
LCs Langerhans cells
HRE hypoxia response element
HIF1 hypoxia-inducible transcription factor
HCC hepatocellular carcinoma
siRNA small interfering RNA
HSCs hepatic stellate cells