AEs	Adverse events
APRF	Acute phase response factor
CXCL1	Chemokine (C-X-C motif) ligand 1
DCs	Dendritic cells
EGFR	Epidermal growth factor receptor
HIF-1α	Hypoxia-inducible factor 1-alpha
ICB	Immune checkpoint blocker
IFN	Interferon
IL	Interleukin
JAK	Janus kinase
K-RAS	Kirsten rat sarcoma viral proto-oncogene
LUAD	Lung adenocarcinoma
MDSCs	Myeloid derived suppressor cells
NF-κB	Nuclear factor-kappa B
NKs	Natural killer cells
nRTK	Non-receptor tyrosine kinase
NSCLC	Non-small cell lung cancer
PD-L1	Programmed cell death 1 ligand 1
PIAS	Protein Inhibitor of Activated Stat
RTK	Receptor tyrosine kinase
SCLC	Small-cell lung cancer
SH2	Src Homology 2
SNPs	Single nucleotide polymorphisms
SOCS	Suppressor of cytokine signaling
STATs	Signal Transducer and Activator of Transcription
TAD	Transactivation domain
TAMs	Tumor-associated macrophages
Th1s	Type 1 CD4+ cells
Th2s	Type 2 CD4+ cells
Th17s +	T helper 17 cells
TKI	Tyrosine kinase inhibitor
TME	Tumor microenvironment
Tregs	regulatory T cells