Figure 1.
Structure of CRBN-binding drugs. (A) Thalidomide. (B) Lenalidomide. (C) Pomalidomide. (D) CC-885. (E) CC-90009 (F) CC-122. (G) CC-220. (H) CC-92480. (I) dBET1, composed of JQ1 (a BRD4 inhibitor) and thalidomide.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.