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. 2020 Jun 8;77(9):1–9. doi: 10.1001/jamaneurol.2020.1568

Figure 2. Relative Contributions of Composite Relapse-Associated Worsening (RAW) and Progression Independent of Relapse Activity (PIRA) vs Overall Composite Confirmed Disability Accumulation (CDA) in Treatment Groups.

Figure 2.

The graphs compare the 12-week confirmed (A and B) and 24-week confirmed (C and D) overall composite CDA. All percentages indicate Kaplan-Meier proportions of patients with confirmed disability accumulation at week 96 in the pooled OPERA I and OPERA II intention-to-treat population.