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. 2020 May 15;12(5):1247. doi: 10.3390/cancers12051247

Figure 4.

Figure 4

Schematic depiction of the number of genes that (inversely) correlate significantly (Spearman’s rank correlation p-value < 0.001) with ex vivo drug response in a single or two or more of the studied drugs (Ara C, VP16, DNR, 2-CdA). A + indicates a positive correlation with high LC50 values, indicating relatively resistant samples. A − indicates a negative correlation with resistance. Overlapping genes are shown, ranked according to the Spearman’s rank correlation coefficient. A maximum of 14 genes are shown. A complete overview of overlapping genes is given in Supplementary Table S3.