Table 4.
List of sequences containing ten cysteines in order of interest for experimental characterization, based on the degree (sequence coverage) in alignment graphs (cf. Figure 2). Name or names of sequences are taken from the Conoserver database [40]. Multiple names for the same sequence indicate the same sequence is produced by different species or has different post-translational modifications. Node degree corresponds to the number of sequences with pairwise alignments that are long enough and have a high enough percent identity to be homology modeled with the given sequence as a template. Cysteines are highlighted in red to guide the eye. We note in the fourth column the pharmacological family, although it is unknown for the majority of sequences, as it requires a separate experimental determination in most cases.
| Sequence | Name(s) | Degree | Pharm. Fam. |
|---|---|---|---|
| DRDVQDCQVSTPGSKWGRCCLNRVCGPMCCPAS– | |||
| HCYCVYHRGRGHGCSC | Cp20.1 | 19 | Unknown |
| LHCYEISDLTPWILCSPEPLCGGKGCCAQEVCD– | |||
| CSGPACTCPPCL | Lt15.6 | 5 | Unknown |
| YNRQCCIDKTYDCLKKYRGRENTFASVCQQEAA– | |||
| VYCGAWDEAEGCCYGYSHCMSMYAQQSGLDVA– | |||
| HNGCKDRKCDNP | Vc21.1 | 2 | Unknown |
| QCTLVNNCDRNGERACNGDCSCEGQICKCGYRV– | |||
| SPGKSGCACTCRNA | Ac8.1 | 2 | Unknown |
| GCSGTCRRHRDGKCRGTCECSGYSYCRCGDAHH– | |||
| FYRGCTCTC | Ca8c | 2 | Unknown |
| TCDPTPDCRTTVCETDTGPCCCPHGYNCQTTNS– | |||
| GRRACVLVCPHNCPP | Pu19.1 | 1 | Unknown |
| SGSTCTCFTSTNCQGSCECLSPPGCYCSNNGIR– | |||
| QRGCSCTCPGT | G8.3 | 1 | Unknown |
| GCTRTCGGPKCTGTCTCTNSSKCGCRYNVHPSG– | |||
| WGCGCACS | GVIIIA | 1 | sigma |
| GCTISCGYEDNRCQGECHCPGKTNCYCTSGHHN– | |||
| KGCGCAC | Tx8.1 | 1 | Unknown |