Abbreviation	Definition
H2AX	Phosphorylated histone H2A member X
ABCB1	ATP Binding Cassette Subfamily B Member 1
ALC1	Amplified in liver cancer protein 1
APLF	Aprataxin and PNKP like factor
APTX	Aprataxin
ATM	Ataxia telangiectasia mutated
ATR	Ataxia telangiectasia and Rad3 related
BARD1	BRCA associated ring domain 1
BER	Base excision repair
BID	Twice a day
BRCA1	Breast cancer 1
BRCA2	Breast cancer 2
CHK1	Checkpoint kinase 1
CSCs	Cancer stem cells
DDR	DNA damage response
DSB	double-strand break
DSD	Double-strand breaks
FDA	Food and Drug Administration
GIS	Genomic instability score
HER2	Human epidermal growth factor receptor 2
HGSOC	High grade serous ovarian cancer
HR	Homologous recombination
LOH	Loss of heterozygosity
LST	Large-scale State Transitions
MDR1	Multidrug resistance 1
MMR	Mismatch repair
MSI	Microsatellite instability
NAD	Nicotinamide adenine dinucleotide
NER	Nucleotide excision repair
NHEJ	HR and non-homologous end-joining
NuRD	Nucleosome remodeling deacetylase
PARG	Poly (ADP) ribose glycohydrolase
PARP	Poly (ADP–ribose) polymerase
PARP1	Poly (ADP–ribose) polymerase 1
PARP2	Poly (ADP–ribose) polymerase 2
PARP3	Poly (ADP–ribose) polymerase 3
PARPi	Poly (ADP–ribose) polymerase inhibitors
PFS	Progression free survival
PNKP	Polynucleotide kinase-phosphatase enzyme
RAD51	RAD51 recombinase
RAD51C	RAD51 recombinase C
RAD51D	RAD51 recombinase D
RCA	Replication Comb Assay
SEER	Surveillance, Epidemiology, and End Results
SGO	Society for Gynecologic Oncology
SigMA	signature multivariate analysis
SSB	Single-strand breaks
TAI	Telomeric Allelic Imbalance
TMB	Tumor mutation burden
XRCC1	X-ray repair cross-complementing 1