Eve |
Everolimus, |
mTOR |
mammalian target of Rapamicin, |
NET |
neuroendocrine tumor, |
RR |
response rate, |
PFS |
progression free survival, |
OS |
overall survival, |
NENs |
neuroendocrine neoplasms, |
WHO |
World Health Organization, |
GEP |
gastro-entero-pancreatic, |
NECs |
neuroendocrine carcinomas, |
FKBP-12 |
FK506 binding protein-12, |
mLST-8 |
mammalian lethal with SEC13 protein 8, |
mTORC-1 and 2 |
mammalian target of Rapamicin Complex 1 and 2, |
mSin-1 |
mammalian stress-activated protein kinase interacting protein 1 |
S6K |
ribosomal protein S6 kinase, |
4EBP1 |
eukaryotic initiation factor 4E-binding protein 1, |
IGF-1 |
insulin growth factor 1, |
IRS-1 |
insulin receptor substrate 1, |
Myc |
myelocytomatosis oncogene cellular homolog, |
HIF-1 |
Hypoxia inducible factor 1, |
pNETs |
pancreatic neuroendocrine tumors, |
DAB |
3’-3-diaminobenzidine, |
RECIST |
response evaluation criteria in solid tumors, |
SSA |
somatostatin analog, |
TACE |
transarterial chemoembolization, |
TSC-1 and 2 |
tuberous sclerosis complex 1 and 2, |
PTEN |
phosphatase and tensin homolog, |
PI3K |
Phosphatidylinositol 3-kinase |
SLE |
Systemic Lupus Erytematosus |