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. 2020 May 10;12(5):1201. doi: 10.3390/cancers12051201
Eve Everolimus,
mTOR mammalian target of Rapamicin,
NET neuroendocrine tumor,
RR response rate,
PFS progression free survival,
OS overall survival,
NENs neuroendocrine neoplasms,
WHO World Health Organization,
GEP gastro-entero-pancreatic,
NECs neuroendocrine carcinomas,
FKBP-12 FK506 binding protein-12,
mLST-8 mammalian lethal with SEC13 protein 8,
mTORC-1 and 2 mammalian target of Rapamicin Complex 1 and 2,
mSin-1 mammalian stress-activated protein kinase interacting protein 1
S6K ribosomal protein S6 kinase,
4EBP1 eukaryotic initiation factor 4E-binding protein 1,
IGF-1 insulin growth factor 1,
IRS-1 insulin receptor substrate 1,
Myc myelocytomatosis oncogene cellular homolog,
HIF-1 Hypoxia inducible factor 1,
pNETs pancreatic neuroendocrine tumors,
DAB 3’-3-diaminobenzidine,
RECIST response evaluation criteria in solid tumors,
SSA somatostatin analog,
TACE transarterial chemoembolization,
TSC-1 and 2 tuberous sclerosis complex 1 and 2,
PTEN phosphatase and tensin homolog,
PI3K Phosphatidylinositol 3-kinase
SLE Systemic Lupus Erytematosus