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. 2020 May 21;12(5):1308. doi: 10.3390/cancers12051308

Figure 3.

Figure 3

Microscopic examination of AGCTs. H&E staining of adult type granulosa cell tumors showing a homogenous cell population with typical grooved, coffee bean-like nuclei. (a) Tumor GCPA011T1.1 with FOXL2 mutation (20× magnification). (b) Tumor GCPA021 (with TERT C228T mutation, DICER1 E1813D and DICER1 stop-gain variant Q1230 *, 20× magnification). (c) and (d) Tumors GCPA016 and GCPA002 with pathogenic TP53 mutation (H179R and C135Y, respectively, 20× magnification). Mitotic activity is indicated by arrows.