Table 2.
Univariate and multivariate Cox proportional analysis regarding CSS in pancreatic cancer patients.
| Variable | Subset | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|
| HR 1 (95% CIl) 2 | p | HR 1 (95% CI) 2 | p | ||
| Gender | Female/Male | 1.159 (0.975–1.377) | 0.94 | 1.003 (0.794–1.266) | 0.98 |
| Grading | G3+4/G1+2 | 1.269 (1.065–1.512) | 0.008 | 1.699 (1.342–2.15) | <0.001 |
| Staging | Stage III/I+II | 3.161 (2.099–4.761) | <0.001 | 2.254 (1.367–3.717) | 0.001 |
| Stage IV/I+II | 3.789 (2.995–4.794) | <0.001 | 3.001 (2.178–4.136) | <0.001 | |
| Chemotherapy | Yes/No | 0.412 (0.339–0.501) | <0.001 | 0.329 (0.251–0.432) | <0.001 |
| Surgical resection | Yes/No | 0.339 (0.775–0.418) | <0.001 | not included | |
| CA 19-9 | >1191.7/≤1191.7 U/mL | 1.872 (1.554–2.256) | <0.001 | 1.288 (1.015–1.635) | 0.037 |
| Bilirubin | >1.9/≤1.9 mg/dL | 0.746 (0.610–0.913) | 0.004 | 0.694 (0.502–0.96) | 0.027 |
| GGT | >25/≤25 U/L | 1.443 (1.093–1.905) | 0.010 | 1.1 (0.711.686) | 0.663 |
| AST | >42/≤42 U/L | 0.880 (0.737–1.052) | 0.160 | 1.017 (0.713–1.45) | 0.925 |
| ALT | >64/≤64 U/L | 0.791 (0.658–0.951) | 0.013 | 0.876 (0.623–1.231) | 0.446 |
| ALP | >70/≤70 U/L | 1.440 (1.101–1.884) | 0.008 | 1.406 (0.937.11) | 0.1 |
| BChE | ≤7272/>7272 U/L | 1.406 (1.129–1.754) | 0.002 | 1.416 (1.10–1.818) | 0.006 |
| PT | >70/≤70% | 0.706 (0.485–1.028) | 0.069 | 0.777 (0.466–1.293) | 0.331 |
Bold values indicate significance (p ≤ 0.05). 1 HR, hazard ratio; 2 CI, confidence interval.