Table 1.
Significant metabolic pathways (False Discovery Rate (FDR) < 0.1) using Homo sapiens as the library.
| Metabolic Pathway | Match Status | Involved Metabolites | p-Value | −Log (p-Value) | False Discovery Rate (FDR) | Pathway Impact Value |
|---|---|---|---|---|---|---|
| Aminoacyl-tRNA biosynthesis (ssc00970) | 9/48 | Alanine, Arginine, Aspartic acid, Glutamic acid, Isoleucine, Methionine, Phenylalanine, Proline, Threonine | 3.55 × 10−7 | 14.85 | 2.98 × 10−5 | 0 |
| Arginine biosynthesis (ssc00220) | 5/14 | Arginine, Aspartic acid, Citrulline, Glutamic acid, Ornithine | 6.53 × 10−6 | 11.94 | 2.74 × 10−4 | 0.48 |
| Arginine and proline metabolism (ssc00330) | 5/38 | Arginine, Glutamic acid, Ornithine, Proline, Pyruvic acid | 1.12 × 10−3 | 6.79 | 0.031 | 0.33 |
| Alanine, aspartate and glutamate metabolism (ssc00250) | 4/28 | Alanine, Aspartic acid, Glutamic acid, Pyruvic acid | 2.72 × 10−3 | 5.91 | 0.057 | 0.42 |