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. 2020 May 16;18(5):261. doi: 10.3390/md18050261

Figure 6.

Figure 6

Regulation of fucosterol on ER stress-sensor proteins in ES2 and OV90 cells. (A-F) Activation of ER-stress-associated response genes, such as IRE1α (A), ATF6α (B), PKR-like ER-resident kinase (PERK) (C), GADD153 (D), eIF2α (E), and GRP78 (F), was analyzed using Western blotting in ES2 and OV90 cells treated with various doses of fucosterol (0, 40, 80, and 100 µM). Intensity of the target protein was detected and analyzed relative to total protein or the TUBA protein. Asterisks indicate significant effects compared to the control (* p < 0.05, ** p < 0.01, and *** p < 0.001).