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. 2020 Apr 30;12(5):1123. doi: 10.3390/cancers12051123

Table 1.

Significant perturbagens class obtained from Connectivity Map. Pharmacologic class of perturbagens reflected with enrichment scores above 90 (similar) and below -90 (opposing) deciphered via Connectivity Map from the hairpin screening for the drug doxorubicin.

CMap Classes Sets of Compound Perturbagens with Enrichment Scores above 90 (Similar) and below -90 (Opposing) Pharmacologic included Drug Numbers
Topoisomerase inhibitor 94.01 16
ATPase inhibitor 92.45 16
TGF beta receptor inhibitor −92.12 4
FGFR inhibitor −94.27 4
Bile acid −94.89 4
MDM inhibitor −99.78 4