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. 2020 Apr 27;12(5):1081. doi: 10.3390/cancers12051081

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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SerpinE1 knockdown reduces GB cell proliferation. (A) A172 or LN18 cell lines were transfected with control siRNA (si-Ctrl) or siRNA for SERPINE1 (si-SERPINE1) and SERPINE1 expression was analyzed by RT-qPCR (t-test, *** p < 0.001). (B,C) Proliferation assays for A172 (B) and LN18 (C) cell lines transfected with siRNA control (si-Ctrl) or siRNA for SERPINE1 (si-SERPINE1) (two-way ANOVA, Bonferroni correction, *** p < 0.001). (D,E) Invasion assays for A172 and LN18 cell lines transfected with siRNA control (si-Ctrl) or siRNA for SERPINE1 (si-SERPINE1). Shown is the percentage of invasion for A172 (D) or LN18 (E) (t-test, * p < 0.05).