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. 2020 May 15;12(5):1252. doi: 10.3390/cancers12051252

Table 1.

Characteristics of triple-negative breast cancer patients.

TNBC Negative BRCA1 BRCA2 p-Value
Number of patients (159) 123 34 2 * **
Mean age at diagnosis (y) 44.78 (24–59) SD 9.07 36.97 (26–54) SD 8.74 45.00 (39–51) SD 8.48 0.004 <0.001
Age group (y) <0.001 <0.001
≤30 5 (4.0%) 9 (26.5%) 0
31–40 31 (25.2%) 13 (38.3%) 1 (50%)
41–50 52 (42.3%) 10 (29.4%) 0
51–60 35 (28.5%) 2 (5.9%) 1 (50%)
Ki 67 (%) 0.508 0.462
≤20 11 (10.1%) 1 (3.3%) 0
>20 98 (89.9%) 29 (96.7%) 1 (100%)
unknown 14 4 1
Bilaterality 0.193 0.088
Yes 5 (4.2%) 4 (12.9%) 0
No 114 (95.7%) 27 (87.1%) 2 (100%)
unknown 4 3 0
Histotype 0.466 0.301
ductal 103 (95.4%) 28 (90.3%) 2 (100%)
lobular 0 1 (3.2%) 0
others 5 (4.6%) 2 (6.5%) 0
unknown 15 3 0
RO 0.321 0.226
negative 116 (95.1%) 30 (88.2%) 2 (100%)
1–9 % 6 (4.9%) 4 (11.8%) 0
unknown 1 0 0

* Comparison Negative vs. BRCA1 vs. BRCA2; ** Comparison Negative vs BRCA1.