Table 1.
TNBC | Negative | BRCA1 | BRCA2 | p-Value | |
---|---|---|---|---|---|
Number of patients (159) | 123 | 34 | 2 | * | ** |
Mean age at diagnosis (y) | 44.78 (24–59) SD 9.07 | 36.97 (26–54) SD 8.74 | 45.00 (39–51) SD 8.48 | 0.004 | <0.001 |
Age group (y) | <0.001 | <0.001 | |||
≤30 | 5 (4.0%) | 9 (26.5%) | 0 | ||
31–40 | 31 (25.2%) | 13 (38.3%) | 1 (50%) | ||
41–50 | 52 (42.3%) | 10 (29.4%) | 0 | ||
51–60 | 35 (28.5%) | 2 (5.9%) | 1 (50%) | ||
Ki 67 (%) | 0.508 | 0.462 | |||
≤20 | 11 (10.1%) | 1 (3.3%) | 0 | ||
>20 | 98 (89.9%) | 29 (96.7%) | 1 (100%) | ||
unknown | 14 | 4 | 1 | ||
Bilaterality | 0.193 | 0.088 | |||
Yes | 5 (4.2%) | 4 (12.9%) | 0 | ||
No | 114 (95.7%) | 27 (87.1%) | 2 (100%) | ||
unknown | 4 | 3 | 0 | ||
Histotype | 0.466 | 0.301 | |||
ductal | 103 (95.4%) | 28 (90.3%) | 2 (100%) | ||
lobular | 0 | 1 (3.2%) | 0 | ||
others | 5 (4.6%) | 2 (6.5%) | 0 | ||
unknown | 15 | 3 | 0 | ||
RO | 0.321 | 0.226 | |||
negative | 116 (95.1%) | 30 (88.2%) | 2 (100%) | ||
1–9 % | 6 (4.9%) | 4 (11.8%) | 0 | ||
unknown | 1 | 0 | 0 |
* Comparison Negative vs. BRCA1 vs. BRCA2; ** Comparison Negative vs BRCA1.