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Inhibition of MDA-MB-231 cell viability by dasatinib, AZD-6244, and their combination. (A) The responses of MDA-MB-231 cells to dasatinib and AZD-6244 are compared to their response to the combination of both at equal molar concentrations; (B) isobolograms of AZD-6244 and dasatinib combination analysis at 50% inhibition; (C) isobolograms of AZD-6244 and dasatinib combination analysis at 70% inhibition. The results are representative of two independent experiments of triplicates.
