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Effects of FASN inhibitors and EGFR TKIs on apoptosis determined by PARP cleavage. Sensitive (PC9) and Gefitinib Resistant (GR) models (PC9-GR1, PC9-GR3, and PC9-GR4) were treated for 72 h with a concentration equivalent to IC50 of each drug. Untreated cells were used as an internal control (Ctrl) and GAPDH as a loading control. Results shown are representative from at least three independent experiments.
