Amygdala Is Excited and SNr Is Inhibited by Motivating Contexts
(A) Foraging task in three different contexts (D/R: 8, S/R: 12, S/P: 12 scenes).
(B–D) Population activity of amygdala neurons (black: D/R, red: S/R, blue: S/P). (B) Activity changes of amygdala neurons during the period including the onsets of scene, fixation point, and object in monkey S. (C) Mean amygdala activity in each context. This was calculated during the period 200 ms before the object onset (shaded yellow area in B). Error bars indicate SEM. (D) Relation between the mean amygdala activity (abscissa) and mean saccade latency (ordinate) (Pearson's correlation) in monkey S. Data are presented separately for individual scenes that are shown in (A).
(E–H) Population activity of SNr neurons that were optogenetically manipulated. E–G, same format as in B–D. (H) Relation between the mean amygdala activity (abscissa) and mean SNr activity (ordinate) for individual scenes (Pearson's correlation).
(I–L) Population activity of SNr neurons that were not optogenetically manipulated. I–K, same format as in B–D. (L) Relation between the mean amygdala activity (abscissa) and mean SNr activity (ordinate) for individual scenes (Pearson's correlation). All neuronal data are for monkey S (Figure S7 for monkey D).