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Superimpositions of all available HAs. A. The rotation of head domain is represented by the 190-helix in the RBS of each HA subtype. The long α helix of the HA2 was used to perform superimposition of different subtype HAs. B. The overlap of interhelix. The PDBs used in the alignment are: H1_1RD8, H1pdm_3M6S, H2_2WRC, H3_4WE4, H5_2FK0, H6_4WST, H7_6D7C, H9_1JSD, H10_4WSX, avH11, H13-4KPQ, avH14, avH15, H16_4F23, H17_4I78, H18_4K3X.
