Table 2.
Univariate regression analysis of factors measured by health check-up (n = 1220, 438 AILD cases vs. 782 healthy controls).
| Factors | Log OR (β) | SE (β) | p value | OR | 95% CI |
|---|---|---|---|---|---|
| Gender (female) | 2.07 | 0.19 | <0.001 | 7.90 | 5.43–11.49 |
| Age at diagnosis (yrs) | 0.07 | 0.01 | <0.001 | 1.07 | 1.05–1.08 |
| GLB (g/L) | 0.30 | 0.02 | <0.001 | 1.35 | 1.30–1.41 |
| ALT (IU/L) | 0.07 | 0.01 | <0.001 | 1.07 | 1.06–1.08 |
| GGT (IU/L) | 0.03 | 0.002 | <0.001 | 1.03 | 1.02–1.03 |
| LN | 2.97 | 0.30 | <0.001 | 19.46 | 10.91–34.69 |
| CEAID | 2.05 | 0.20 | <0.001 | 7.75 | 5.27–11.39 |
| FA | 2.80 | 0.28 | <0.001 | 16.50 | 9.53–28.55 |
Log OR (β): logistic regression β coefficients (log odds ratio for one unit increase in the explanatory variable); SE (β): standard error for the β coefficient; OR: odds ratio for one unit increase in the explanatory variable (exponential of β); 95% CI: 95% confidence interval for the odds ratio; Abbreviations: AILD: autoimmune liver disease; GLB: globulin; ALT: alanine aminotransferase; GGT: γ-glutamyltransferase; LN: abdominal lymph node enlargement (B-mode ultrasound); CEAID: current extrahepatic autoimmune diseases; FA: familial autoimmunity.