Table 2.
Treatment planning (PTVWB-A = Planning target volume of the whole brain in arm A, PTVWB-B = Planning target volume of the whole brain in arm B, PTVmet = Planning target volume of metastases)
| Radiation treatment planning | PTVWB- A or -B | PTVmet | Major deviations |
|---|---|---|---|
| Prescribed total dose to PTV | 30 Gy |
51Gy (brain stem metastasis and resection cavity: 42Gy) |
< or > 30Gy for PTVWB-A or -B < or > 51Gy for PTVmet (brain stem metastasis and resection cavity: < or > 42Gy) |
| Prescribed dose per fraction in PTV | 2.5 Gy |
4.25Gy (brain stem metastasis and resection cavity: 3.5Gy) |
< or > 2.5Gy for PTVWB-A or -B < or > 4.25Gy for PTVmet (brain stem metastasis and resection cavity: 3.5Gy) |
| Number of fractions per day | 1 | 1 | > 1 |
| Treatment duration |
12 days 5 days/week |
12 days 5 days/week |
< or > 12 days < 4 or > 5 days/week |