Table IV.
Expression of NLRP3, ASC and caspase-1 mRNA in peripheral blood mononuclear cells.
Group | n | NLRP3 | ASC | Caspase-1 |
---|---|---|---|---|
Control | 15 | 23.54±1.19 | 25.88±1.18 | 26.99±1.43 |
Hyperuricemia | 15 | 26.05±1.89a | 27.49±3.56a | 28.05±2.41a |
Gouty nephropathy | 15 | 25.43±1.66a | 32.21±3.01a,c | 30.80±2.80a,b |
Values are presented as the mean ± standard deviation.
aP<0.01 vs. the control group;
bP<0.05 vs. the hyperuricemia group;
cP<0.01 vs. the hyperuricemia group; NLRP3, nucleotide-binding domain and leucine-rich repeat protein 3; ASC, apoptosis-associated speck like protein.