Table 1.
Baseline characteristics of the study population
| Total (n = 73) | Early stage of lung cancer (n = 38) | Advanced stage of lung cancer (n = 35) | |
|---|---|---|---|
| Age (year) | 65.3 ± 9.8 | 65.0 ± 8.1 | 65.7 ± 11.5 |
| Sex (F/M) | 35/38 (47.9/52.1) | 20/18 (52.6/47.4) | 15/20 (42.9/57.1) |
| Smoking status | |||
| Never smoker | 45 (61.6) | 25 (65.8) | 20 (57.1) |
| Former smoker | 22 (30.1) | 10 (26.3) | 12 (34.3) |
| Current smoker | 6 (8.2) | 3 (7.9) | 3 (8.6) |
| Smoking amount (pack-year) | 12.6 ± 21.4 | 11.3 ± 20.0 | 14.1 ± 23.2 |
| Tumor type | |||
| Adenocarcinoma | 65 (89.0) | 32 (84.2) | 33 (94.3) |
| Squamous cell carcinoma | 7 (9.6) | 5 (13.2) | 2 (5.7) |
| Sarcomatoid carcinoma | 1 (1.4) | 1 (2.6) | – |
| Tumor size (cm) | 3.5 ± 2.0 | 3.0 ± 2.0 | 3.9 ± 1.9 |
| Lung cancer stage | |||
| I/II/III/IV | 26/10/10/27 | 26/10/2/− | −/−/8/27 |
| EGFR genotyping | |||
| Wild type | 35 (47.9) | 18 (47.4) | 17 (48.6) |
| E19del | 19 (26.0) | 12 (31.6) | 7 (20.0) |
| L858R | 19 (26.0) | 8 (21.1) | 11 (31.4) |
Note: Early stage refers to stage I - IIIA, and advanced stage refers to stage IIIB - IV
Abbreviation: E19del, (c.2235del15; p.E746_A750del); L858R, (c.2573 T > G; p.Leu858Arg)