Table 2.
Sensitivity, specificity, and concordance rate of ddPCR according to EGFR mutation
| L858R | E19del | |||||
|---|---|---|---|---|---|---|
| Plasma | BWF | p-value | Plasma | BWF | p-value | |
| AUC |
0.717 (0.592–0.842) |
0.961 (0.901–1.0) |
< 0.001 |
0.632 (0.519–0.745) |
0.858 (0.746–0.969) |
< 0.001 |
| Sensitivity (%) | 47.37 | 89.47 | 31.58 | 68.42 | ||
| Specificity (%) | 98.15 | 96.30 | 94.44 | 98.15 | ||
| Concordance rate | 82.2% (60/73) | 94.5% (69/73) | 76.7% (56/73) | 84.9% (62/73) |
Abbreviation: BWF, bronchial washing fluid; AUC, area under curve; E19del, (c.2235del15; p.E746_A750del); L858R, (c.2573 T>; p.Leu858Arg)