Table II.
KEGG analysis of differentially expressed genes (top 5 according to P-value).
| A, Upregulated genes | ||
|---|---|---|
| Term | Count | P-value |
| hsa01100:Metabolic pathways | 107 | 2.83x10-14 |
| hsa05204:Chemical carcinogenesis | 21 | 9.07x10-11 |
| hsa00830:Retinol metabolism | 17 | 7.29x10-9 |
| hsa04610:Complement and coagulation cascades | 17 | 2.35x10-8 |
| hsa00980:Metabolism of xenobiotics by cytochrome P450 | 17 | 6.78x10-8 |
| B, Downregulated genes | ||
| Term | Count | P-value |
| hsa04110:Cell cycle | 21 | 6.49x10-15 |
| hsa04512:ECM-receptor interaction | 11 | 1.44x10-6 |
| hsa04115:p53 signaling pathway | 9 | 1.28x10-5 |
| hsa05200:Pathways in cancer | 20 | 2.06x10-5 |
| hsa03030:DNA replication | 7 | 2.36x10-5 |
KEGG, Kyoto Encyclopedia of Genes and Genomes; hsa, Homo sapiens; ECM, extracellular matrix.