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. 2020 May 8;20(1):550–560. doi: 10.3892/etm.2020.8733

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Copyright: © Geng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of rosuvastatin on the phosphorylation of PERK and eIF2α in HUVECs induced by ox-LDL. (A) The expression of p-PERK and p-eIF2α in HUVECs. (B and C) The densitometric analysis of p-PERK and p-eIF2α, which expressed as the ratio of p-PERK/p-eIF2α to total PERK/eIF2α. GAPDH was the loading control. The densitometric analysis values expressed as the mean ± standard deviation. ^**P<0.01 vs. control group; ^##P<0.01 vs. ox-LDL group. PERK, protein kinase RNA-like ER kinase; eIF2α, inositol-requiring protein 1α; HUVECs, human umbilical vascular endothelial cells; ox-LDL, oxidized low density lipoprotein; p-, phosphorylated.