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. 2020 May 8;20(1):550–560. doi: 10.3892/etm.2020.8733

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Copyright: © Geng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of rosuvastatin on the expression of GRP78 and p-IRE1α in HUVECs induced by ox-LDL. (A) The expression of GRP78 and p-IRE1α in HUVECs. (B and C) The densitometric analysis of GRP78 and p-IRE1α, the phosphorylation of IRE1α expressed as the ratio of p-IRE1α to total IRE1α. GAPDH was the loading control and the subjacent band is the target band of GRP78. The densitometric analysis values expressed as the mean ± standard deviation. ^**P<0.01 vs. control group; ^#P<0.05 vs. ox-LDL; ^##P<0.01 vs. ox-LDL group. GRP78, glucose-regulated protein 78; p-, phosphorylated; IRE1α, p-inositol-requiring protein 1α; HUVECs, human umbilical vascular endothelial cells.