Table 2.
Prevalence of SNPs in pfk13, pfcoronin, pfcrt, and pfmdr1 in Pakistan, 2018–2019
| Gene | N | Wild Typea N (%) | Mutantb N (%) | Mixedc N (%) |
|---|---|---|---|---|
| Pfk13 | 121 | 121 (100) | 0 (0) | 0 (0) |
| Pfcoronin | 149 | 149 (100) | 0 (0) | 0 (0) |
| Pfmdr1 N86Y | 179 | 137 (76.5) | 29 (16.2) | 13 (7.3) |
| Pfmdr1 Y184F | 172 | 143 (83.1) | 18 (10.5) | 11 (6.4) |
| Pfmdr1 D1246Y | 173 | 173 (100) | 0 (0) | 0 (0) |
| Pfcrt K76T | 179 | 3 (1.7) | 164 (91.2) | 12 (6.7) |
a Wild type alleles include Pfmdr1 N86, Y184, D1246, and Pfcrt K76
b Mutant alleles include Pfmdr1 86Y, 184F, 1246Y, and Pfcrt 76T
c Mixed alleles include Pfmdr1 N86Y, Y184F, D1246Y and Pfcrt K76T mixed infections