Table 2.
Crude and adjusted odds ratios for outcomes associated with paternal age, maternal age and fetal sex (total live births = 1,347,672)
| Gestational hypertension or preeclampsia (n = 30,526) | Eclampsia (n = 944) | Preterm birth (n = 92,663) | ||||
|---|---|---|---|---|---|---|
| Crude OR (95% CI) | Adjusted OR (95% CI)a | Crude OR (95% CI) | Adjusted OR (95% CI)a | Crude OR (95% CI) | Adjusted OR (95% CI)a | |
| Paternal age | ||||||
| < 25 | 0.98 (0.92, 1.04) | 1.00 (0.94, 1.07) | 1.45 (1.09, 1.94)+ | 1.37 (1.01, 1.85)+ | 1.14 (1.11, 1.18)+ | 1.05 (1.01, 1.09)+ |
| 25–29 (ref) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| 30–34 | 1.05 (1.02, 1.09)+ | 1.01 (0.98, 1.05) | 1.18 (0.99, 1.41) | 1.18 (0.97, 1.43) | 1.02 (1.00, 1.04)+ | 1.03 (1.01, 1.05)+ |
| 35–39 | 1.24 (1.20, 1.28)+ | 1.08 (1.04, 1.13)+ | 1.17 (0.96, 1.42) | 1.10 (0.86, 1.41) | 1.14 (1.12, 1.16)+ | 1.09 (1.06, 1.12)+ |
| 40–44 | 1.58 (1.51, 1.65)+ | 1.26 (1.19, 1.33)+ | 1.85 (1.45, 2.36)+ | 1.59 (1.17, 2.16)+ | 1.33 (1.30, 1.37)+ | 1.19 (1.15, 1.23)+ |
| 45–49 | 1.73 (1.60, 1.87)+ | 1.42 (1.31, 1.55)+ | 1.81 (1.17, 2.79)+ | 1.53 (0.94, 2.49) | 1.39 (1.33, 1.46)+ | 1.25 (1.18, 1.32)+ |
| ≥ 50 | 1.67 (1.46, 1.90)+ | 1.60 (1.39, 1.84)+ | 2.25 (1.16, 4.39)+ | 2.14 (1.05, 4.38)+ | 1.44 (1.32, 1.57)+ | 1.38 (1.27, 1.51)+ |
| Maternal age | ||||||
| < 20 | 0.93 (0.85, 1.03) | 0.89 (0.80, 0.99)+ | 1.31 (0.81, 2.11) | 1.06 (0.65, 1.74) | 1.35 (1.29, 1.42)+ | 1.25 (1.19, 1.32)+ |
| 20–24 | 0.89 (0.86, 0.93)+ | 0.89 (0.86, 0.94)+ | 1.07 (0.86, 1.32) | 1.00 (0.79, 1.26) | 1.02 (1.00, 1.04) | 1.00 (0.97, 1.02) |
| 25–29 (ref) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| 30–34 | 1.18 (1.15, 1.21)+ | 1.19 (1.15, 1.23)+ | 1.21 (1.03, 1.41)+ | 1.22 (1.02, 1.45)+ | 1.09 (1.07, 1.11)+ | 1.10 (1.08, 1.12)+ |
| 35–39 | 1.69 (1.63, 1.75)+ | 1.60 (1.53, 1.67)+ | 1.54 (1.26, 1.88)+ | 1.48 (1.14, 1.91)+ | 1.39 (1.36, 1.42)+ | 1.34 (1.30, 1.37)+ |
| ≥ 40 | 2.76 (2.58, 2.94)+ | 2.31 (2.14, 2.49)+ | 3.07 (2.18, 4.31)+ | 2.44 (1.64, 3.63)+ | 1.91 (1.82, 1.99)+ | 1.70 (1.62, 1.79)+ |
| Fetal sex | ||||||
| Boy vs Girl | 0.95 (0.93, 0.97)+ | 0.95 (0.93, 0.97)+ | 0.80 (0.71, 0.91)+ | 0.80 (0.71, 0.91)+ | 1.24 (1.22, 1.25)+ | 1.24 (1.22, 1.25)+ |
CI confidence interval, OR odds ratio
aAdjusted for paternal age, maternal age, maternal nationality (Taiwanese or not), income (four categories) and fetal sex
+P-value < 0.05