Table 1.

Main characteristics of included studies

Study	Year	Country	Ethnicity	Gender	Sample size	Case				Control			HWE
						DD	DI	II		DD	DI	II
Hu XJ	2019	China	Asian	Both	182/307	36	81	65		40	147	120	0.63
Jin SY	2019	China	Asian	Both	778/1112	140	387	251		157	529	426	0.72
Coto E	2019	Spain	Caucasian	Male	609/423	91	291	227		59	201	163	0.81
Seidi A	2018	Iran	Asian	Both	124/100	27	50	47		9	38	53	0.57
Luo JY	2017	China	Asian	Both	1184/1112	215	562	407		157	529	426	0.72
Lai HM	2015	China	Asian	Both	960/1060	178	425	357		131	492	437	0.70
Lai H	2015	China	Asian	Both	1140/1156	218	530	392		154	561	441	0.24
Arslan S	2015	Turkey	Asian	Both	226/201	36	114	76		20	96	85	0.34
Mishra A	2014	India	Asian	Both	510/230	46	166	298		15	68	147	0.07
Yang YN (I)	2014	China	Asian	Both	633/616	126	282	225		103	291	222	0.64
Yang YN (II)	2014	China	Asian	Both	437/356	70	195	172		48	161	147	0.71
Stegger JG (I)	2013	Denmark	Caucasian	Both	1012/1719	171	484	357		255	792	672	0.39
Stegger JG (II)	2013	USA	Caucasian	Male	427/873	57	216	154		140	389	344	0.09
Stegger JG (III)	2013	USA	Caucasian	Female	471/922	75	213	183		148	412	362	0.09
Mishra A (I)	2013	India	Asian	Both	310/230	27	96	187		15	68	147	0.07
Mishra A (II)	2013	India	Asian	Both	290/230	28	99	163		15	68	147	0.07
Xie FY	2008	China	Asian	Both	85/88	18	41	26		22	41	25	0.53

HWE Hardy-Weinberg Equilibrium