Table 4. The association between different asbestos-related diseases and genotypes in univariate analysis.
Polymorphism | Genotype | Pleural plaques vs no disease | Asbestosis vs no disease | MM vs no disease | MM vs pleural plaques | ||||
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | ||
CARD8 rs2043211 | AA | reference | reference | reference | reference | ||||
p.Cys10Ter | AT | 1.48 (0.99–2.21) | 0.058 | 1.19 (0.74–1.92) | 0.469 | 1.18 (0.73–1.90) | 0.508 | 0.80 (0.54–1.18) | 0.252 |
TT | 1.49 (0.81–2.73) | 0.201 | 1.00 (0.48–2.11) | 1.000 | 0.77 (0.35–1.69) | 0.506 | 0.52 (0.27–1.00) | 0.049 | |
AT+TT | 1.48 (1.01–2.16) | 0.042 | 1.15 (0.73–1.80) | 0.545 | 1.08 (0.69–1.70) | 0.735 | 0.73 (0.50–1.06) | 0.099 | |
NLRP3 rs35829419 | CC | reference | reference | reference | reference | ||||
p.Gln705Lys | CA+AA | 0.95 (0.51–1.77) | 0.861 | 0.92 (0.43–1.95) | 0.822 | 1.34 (0.66–2.74) | 0.416 | 1.42 (0.80–2.52) | 0.229 |