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. 2020 Jan 10;39(1):91-99. doi: 10.2478/jomb-2019-0025

Table 4. The association between different asbestos-related diseases and genotypes in univariate analysis.

Polymorphism Genotype Pleural plaques vs no disease Asbestosis vs no disease MM vs no disease MM vs pleural plaques
OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P
CARD8 rs2043211 AA reference reference reference reference
p.Cys10Ter AT 1.48 (0.99–2.21) 0.058 1.19 (0.74–1.92) 0.469 1.18 (0.73–1.90) 0.508 0.80 (0.54–1.18) 0.252
TT 1.49 (0.81–2.73) 0.201 1.00 (0.48–2.11) 1.000 0.77 (0.35–1.69) 0.506 0.52 (0.27–1.00) 0.049
AT+TT 1.48 (1.01–2.16) 0.042 1.15 (0.73–1.80) 0.545 1.08 (0.69–1.70) 0.735 0.73 (0.50–1.06) 0.099
NLRP3 rs35829419 CC reference reference reference reference
p.Gln705Lys CA+AA 0.95 (0.51–1.77) 0.861 0.92 (0.43–1.95) 0.822 1.34 (0.66–2.74) 0.416 1.42 (0.80–2.52) 0.229