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. 2020 Jan 10;39(1):91-99. doi: 10.2478/jomb-2019-0025

Table 3. Genotype frequencies of investigated polymorphisms in asbestos-exposed subjects.

Missing data are presented in square brackets [].

Polymorphism Genotype All subjects (N=879) N (%) No disease (N=149) N (%) Pleural plaques (N=416) N (%) Asbestosis (N=160) N (%) Malignant mesothelioma (N=154)
CARD8 rs2043211 AA 389 (44.5) [4] 74 (50.0) 167 (40.3) [2] 74 (46.5) [1] 74 (48.1)
p.Cys10Ter AT 382 (43.7) 57 (38.5) 190 (45.9) 68 (42.8) 67 (43.5)
TT 104 (11.9) 17 (11.5) 57 (13.8) 17 (10.7) 13 (8.4)
NLRP3 rs35829419 CC 785 (89.7) [4] 133 (89.9) [1] 375 (90.4) [1] 145 (90.6) 132 (86.8) [2]
p.Gln705Lys CA 88 (10.1) 15 (10.1) 39 (9.4) 14 (8.8) 20 (13.2)
AA 2 (0.2) 0 1 (0.2) 1 (0.6) 0