Table 3.
Correlation of disease severity in the proximal small bowel, terminal ileum, and colon using CE versus MRE plus IC based on Lewis, SES-CD, and MaRIA scores
| CE score | Kappa (95% CI) | P value | ||||||
| Proximal small bowel Lewis Score | ||||||||
| Absent | Mild | Moderate/severe | Total | |||||
| MRE | MaRIA score | Absent | 35 (36%) | 12 (12%) | 6 (6%) | 53 (54%) | 0.105 (−0.046 to 0.257) | 0.153 |
| Mild | 12 (12%) | 7 (7%) | 6 (6%) | 25 (26%) | ||||
| Moderate/severe | 12 (12%) | 3 (3%) | 5 (5%) | 20 (20%) | ||||
| Total | 59 (60%) | 22 (22%) | 17 (17%) | 98 (100%) | ||||
| Terminal ileum SES-CD | ||||||||
| Absent | 13 (14%) | 12 (13%) | 1 (1%) | 26 (29%) | 0.009 (−0.097 to 0.080) | 0.849 | ||
| Mild | 9 (10%) | 5 (6%) | 1 (1%) | 15 (17%) | ||||
| Moderate | 6 (7%) | 5 (6%) | 0 | 11 (12%) | ||||
| Severe | 6 (7%) | 22 (24%) | 10 (11%) | 38 (42%) | ||||
| Total | 34 (38%) | 44 (49%) | 12 (13%) | 90 (100%) | ||||
| IC | SES-CD | Terminal ileum SES-CD | ||||||
| Absent | 28 (34%) | 10 (12%) | 0 | 38 (46%) | <0.001 | 0.579 (0.423 to 0.736) | ||
| Mild | 3 (4%) | 30 (37%) | 4 (5%) | 37 (45%) | ||||
| Moderate | 1 (1%) | 2 (2%) | 4 (5%) | 7 (9%) | ||||
| Total | 32 (39%) | 42 (51%) | 8 (10%) | 82 (100%) | ||||
| Colon SES-CD | ||||||||
| Absent | 52 (59%) | 8 (9%) | 0 | 60 (68.2%) | <0.001 | 0.440 (0.260 to 0.619) | ||
| Mild | 9 (10%) | 14 (16%) | 1 (1%) | 24 (27%) | ||||
| Moderate | 0 | 4 (5%) | 0 | 4 (5%) | ||||
| Total | 61 (69%) | 26 (30%) | 1 (1%) | 88 (100%) | ||||
*Lewis score <135=absent, 135≤ Lewis Score ≤790=mild, and >790=moderate or severe; SES-CD index 0–2=absent, 3–6=mild, 7–15=moderate, and >15=severe; MaRIA score <7=inactive, 7–9=mild, >9–11=moderate, and >11=severe.
CE, capsule endoscopy; IC, ileocolonoscopy; MaRIA, Magnetic Resonance Index of Activity; MRE, magnetic resonance enterography; SES-CD, Simple Endoscopic Score for Crohn’s Disease.