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. 2020 Jun 7;10(6):e036374. doi: 10.1136/bmjopen-2019-036374

Table 3.

Total ACE-attributable DALYs and costs and sensitivity analyses

ACE-attributable DALYs (thousands) ACE-attributable costs
(£ billion)
Equivalent % of GVA
England Wales England and Wales England Wales England and Wales England Wales England and Wales
Best estimate 1444.9 110.0 1554.9 40.6 2.2 42.8 2.6 3.5 2.6
Limited to DALYs for individuals aged 15–69 years old 956.4 69.5 1025.8 26.9 1.4 28.3 1.7 2.2 1.7
PAFs generated using lower CIs for RRs 546.7 47.7 594.4 15.4 0.9 16.3 1.0 1.5 1.0
PAFs generated using upper CIs for RRs 2314.3 169.0 2483.2 65.0 3.4 68.4 4.2 5.4 4.2
Lower bound (uncertainty interval) for DALYs 1273.7 96.0 1369.8 35.8 1.9 37.7 2.3 3.1 2.3
Upper bound (uncertainty interval) for DALYs 1638.6 126.0 1764.7 46.0 2.5 48.5 2.9 4.0 3.0

ACE, adverse childhood experience; DALY, disability adjusted life year; GVA, gross value added; PAF, population attributable fraction; RR, risk ratio.