Table 3.

Cox multivariable regression of independent predictors of survival in patients with stage IB LCNEC treated with or without adjuvant therapy

		95% Confidence Interval
Predictor	Hazard Ratio	Lower	Upper	p-value
Age (per year)	1.01	1.00	1.03	0.056
Female sex	0.92	0.73	1.15	0.445
Race
White	Ref	Ref	Ref	Ref
Black	1.02	0.68	1.54	0.907
Other	0.39	0.12	1.29	0.124
Charleson-Deyo Comorbidity Index
0	Ref	Ref	Ref	Ref
1	0.85	0.66	1.10	0.222
2+	1.26	0.93	1.71	0.131
Year of diagnosis (per year)	0.98	0.94	1.02	0.226
Insurance status
Private	Ref	Ref	Ref	Ref
Government	1.81	1.34	2.45	< 0.001
None	1.04	0.44	2.46	0.925
Facility location
Metro	Ref	Ref	Ref	Ref
Urban	1.07	0.81	1.41	0.653
Rural	0.95	0.61	1.50	0.835
Facility type
Community Cancer Program	Ref	Ref	Ref	Ref
Comprehensive Community Cancer Program	0.76	0.49	1.18	0.216
Academic/Research Program	0.96	0.61	1.53	0.869
Integrated Network Cancer Program	0.99	0.59	1.65	0.963
Surgery
Wedge resection	Ref	Ref	Ref	Ref
Segmental resection	1.38	0.70	2.71	0.355
Lobectomy	0.63	0.43	0.93	0.020
Pneumonectomy	0.53	0.20	1.38	0.191
Adjuvant therapy
None	Ref	Ref	Ref	Ref
Chemotherapy	0.67	0.5	0.9	0.007
Chemoradiation	1.55	0.84	2.85	0.163
Radiation	2.05	1.03	4.07	0.041