Table 3.

Adverse events in each therapy group

Adverse event	VA-dual (n=168)	VAC-triple (n=167)	P value
Diarrhoea	16 (9.5%)	25 (15.0%)	0.128
Moderate	1	3
Bloating	20 (11.9%)	14 (8.4%)	0.286
Moderate	1	0
Constipation	10 (6.0%)	8 (4.8%)	0.637
Skin rash	9 (5.4%)	5 (3.0%)	0.280
Moderate	4	1
Nausea	5 (3.0%)	4 (2.4%)	0.742
Moderate	0	1
Abdominal pain	6 (3.6%)	2 (1.2%)	0.155
Moderate	1	0
Dysgeusia	3 (1.8%)	3 (1.8%)	0.994
Oral mucositis	0	6 (3.6%)	0.013
Others	2 (1.2%)	2 (1.2%)	0.995
Total patients	46 (27.4%)	51 (30.5%)	0.524

VAC-triple, vonoprazan, amoxicillin and clarithromycin triple therapy; VA-dual, vonoprazan and amoxicillin dual therapy.