Table 2. Summary of the homologous (Ig (G+M), IgG1, IgG (2a+2b), IgA) and heterologous (Ig (G+M)) antibody responses after the last immunization with SipD or IpaD by the IN and IG routes.
Homologous antibody response | Heterologous response | |||||
---|---|---|---|---|---|---|
Immunization route | Immunogen | Ig(G+M) | IgG1 | IgG(2a+2b) | IgA titer | Ig (G+M) |
IN | SipD | 1.7 x 103 | 2.6 x 103 | 4.6 x 102 | 2.4 x 102 | 4.4 x 101 |
IpaD | 2.9 x 104 | 2.0 x 104 | 6.8 x 103 | 5.2 x 102 | 2.9 x 101 | |
IG | SipD | 1.2 x 103 | 6.8 x 103 | 9.9 x 102 | 1.7 x 102 | 4.4 x 100 |
IpaD | 2.6 x 104 | 4.9 x 102 | 8.3 x 103 | 3.8 x 102 | 1.9 x 102 |
Data represent mean concentrations (ng/mL) for Ig(G+M), IgG1, IgG(2a+2b) responses and IgA titer from each group of mice.