Fig. 2.

a) Alignment of the primary sequences the S1-NTDs of SARS-CoV-2, SARS-CoV and Bat-CoV RatG13 isolate. b) A cartoon presentation of 3D structure model of the SARS-CoV-2 S1-NTD with the four inserts identified in (a) shown as sticks: insert 1 colored in red, insert 2 colored in magenta, insert 3 colored in green and insert 4 colored in blue. c) A cartoon representation of the SARS-CoV-2 spike trimer showing the orientation of the S1-NTD towards the outside environment; the different inserts shown as sticks and colored as described in (b).