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. 2020 Jun 9;286:198058. doi: 10.1016/j.virusres.2020.198058

Fig. 6.

Fig. 6

a) Surface representation of the S protein trimers of IBV (PDB ID: 6CV0), MERS-CoV (PDB ID: 5 × 5F), SARS-CoV (PDB ID: 5 × 58), and MHV (PDB ID: 3JCL); chains A, B and C are colored in cyan, blue and magenta, respectively; the protruding 511TNGTRRF517 motif in the IBV trimer is colored in yellow in chains A and B. b) The folylpolyglutamate synthetase (FPGS) of Lactobacillus casei (PDB ID: 1FGS), with the putative nucleotide-binding P loop, harboring the 42IHVTGTNG49 motif, is shown in red, the Ω loop is shown in yellow, and the ligand is shown as magenta spheres. c) A top view of the SARS-CoV-2 S1-NTD showing the adjacent 72GTNGTKR78 (insert 1) and 254SSSG257 (insert 4) loops in red and yellow respectively. d) Structural alignment of the IHVxGTNG loops of SARS-CoV-2 S1-NTD (blue) and FPGS (yellow).