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. 2020 May 26;9:e54903. doi: 10.7554/eLife.54903

Scheme 1. Schema depicting the prenatal roles of Maf and Mafb.

Scheme 1.

In Pai et al., 2019, we described that the expression of Maf and Mafb starts in the MGE SVZ. Deletion of Maf and Mafb using the Nkx2.1-Cre (Maf cDKO) leads to increased neurogenesis in the MGE SVZ and overproduction of somatostatin (SST) interneurons. In this paper, we aim to identify the downstream gene targets of Maf and Mafb that are involved in this process. SVZ: subventricular zone. MZ: mantle zone.