. Author manuscript; available in PMC: 2020 Jun 9.

Published in final edited form as: Mult Scler Relat Disord. 2019 Jan 31;30:192–197. doi: 10.1016/j.msard.2019.01.055

Table 5.

ROC analyses identifying optimal cut-off scores for the PHQ-8 and FSS with regard to identifying Underestimators.

Test	Cut-Off^*	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
PHQ-8	≥6	74	66	49	85
FSS	≥36	77	64	49	86

Notes. N = 99 participants.

Cut-off scores represent optimal balance between sensitivity and specificity based on Youden’s index.

Abbreviations: FSS = Fatigue Severity Scale; NPV = negative predicted value; PHQ-8 = Patient Health Questionnaire-8; PPV = positive predicted value.